Music review: Closer — I Hate This Place | 4/5

I Hate This Place is a Singapore-based electro-pop project that Sean Nerney set up back in 2004. Since 2007, I Hate This Place has had CDs released in Japan and has toured extensively across the Land of the Rising Sun. Despite this, it has remained relatively under the radar at home (notwithstanding a back catalogue of seven full albums). Hopefully, this situation will now change with the release of Closer. With reinforcements coming in the form of singer Gayle Nerva and guitarist Roman Tarrasov, I Hate This Place has delivered an appealing work of dancey, melodic electro-pop. At eleven tracks (including two updated versions of crowd favourites Rabbit Girl and Future Girl Retro Style), Closer is an accurate snapshot of where it stands circa 2013. Songs like Danger and Supernova are radio-friendly poles of extremes in the repertoire — the former being an edgy rocker while the latter is a pleasing ballad. The chemistry of the vocal interplay between Nerney and Nerva is nothing short of mesmerising and Tarrasov’s guitar licks will please the rock set. Fans of Postal Service, Owl City, Lights, Shiny Toy Guns, and Swimming With Dolphins will find much to appreciate here. I believe it’s time for Singapore music fans to get better acquainted with I Hate This Place.

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Catalysts' outer coordination spheres take their place in the spotlight

Wendy Shaw wrote a comprehensive review article on outer coordination spheres.

(Phys.org) —Once dismissed as shrubbery, experimental and computational research shows the outer coordination sphere greatly influences a catalyst's effectiveness, according to Dr. Wendy Shaw at Pacific Northwest National Laboratory in her invited review article. The outer coordination sphere is the complex structure that wraps around the catalyst's central active site and controls the activity, selectivity and specificity of the catalyst. Shaw's Catalysis Reviews article focuses on bottom-up design research. In this approach, aspects of the outer coordination sphere are added as needed.

"The advantage is that you can add just the features you need to get the effects you want," said Shaw.

In her article, Shaw explores studies of a minimal outer coordination sphere based on amino acids. She goes beyond these simple arrangements to examine structured peptide use. These more complex structures allow scientists to add specific positioning of an amino acid near the active site to change the molecular properties at the metal, controlling the catalyst's behavior. She also examines the newer area of enzyme mimics. She notes several exciting studies are using computers to design enzymes from scratch that catalyze reactions that aren't found in nature.

Looking back at the 61-page review, with 226 references, she notes that many of the catalysts fall into two categories: those that function but have undefined outer coordination spheres and those that do not work but have rigorously defined spheres. Few, such as a PNNL rhodium-based catalyst, perform the task at hand and have defined structures. For her, the takeaway message is the large influence that changes far from the active site can exert over the reactivity of the catalyst, and the power of integrating computational chemistry and experimentation to create functional and structurally characterized catalysts.

More information: Shaw WJ. 2012. The Outer-Coordination Sphere: Incorporating Amino Acids and Peptides as Ligands for Homogeneous Catalysts to Mimic Enzyme Function. Catalysis Reviews 54(4):489-550. DOI: 10.1080/01614940.2012.679453

Provided by Pacific Northwest National Laboratory

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